In the past few years, great strides have been made in the field of personalized medicine; targeted therapies, such as antibody-drug conjugates, are on the forefront of next generation technologies that are anticipated to revolutionize the cancer treatment landscape. These therapies are theoretically capable of overcoming the setbacks associated with cytotoxic chemotherapeutics that are known to kill or damage healthy cells as well.
The domain has witnessed a gradual increase in clinical research activity over the last few years. This can be attributed to various initiatives undertaken by several industry and non-industry players, which are actively evaluating the efficacy of antibody drug conjugates for a wide range of indications.
The global antibody drug conjugate market, valued at USD 12.30 billion in 2024, is projected to reach USD 15.29 billion in 2025 and USD 28.41 billion by 2035, representing a CAGR of 6.4% during the forecast period.
The maximum number of trials (49%) registered for the evaluation of antibody drug conjugates were / are being conducted in Asia-Pacific. Within this region, most of the trials were / are being conducted in China, followed by Korea and Japan. Further, in North America, the majority of the trials were / are being conducted in the US. In Europe, the highest number of trials were / are being conducted in Spain. Further, the maximum clinical trials focused on evaluating antibody drug conjugates are actively recruiting. This can be attributed to the fact that most of the ADCs developed so far are for treating cancer; however, our estimates and market trends suggest that there is enormous potential for using ADCs to treat other diseases. This has eventually encouraged patients to participate in these clinical trials to obtain favorable treatment outcomes from the antibody-drug conjugates therapies. In addition, it is worth noting that there have been an active support from regulatory authorities in approving the candidates in ADC pipeline, subsequently leading to higher patient recruitment. Besides the above trials that are actively recruiting, there are close to 120 trials that are not yet recruiting, followed by trials that have been completed and trials that are active, however not recruiting.
The estimated opportunity associated with the antibody drug conjugates market is expected to well-distributed across different market segmentation including target indication, therapeutic area, linker, payload, target antigen, geographical regions and sales forecast of therapies. Using our proprietary methodology, we have provided informed projections, describing the likely growth of the opportunity associated with the antibody drug conjugates market. As per the base case forecast scenario, the antibody drug conjugates market is estimated to grow at an annualized rate of ~6.5%, during the forecast period 2025 to 2035. It is worth mentioning that according to projections, the antibody drug conjugates market in North America is likely to capture majority (62%) of the overall market share, and this trend is unlikely to change in the future, as well. Further, it is worth noting that the market in Asia-Pacific and the rest of the world is expected to grow at a relatively faster pace during the forecast period. Furthermore, the global market opportunity is expected to be well-distributed across different market segmentations including target indication, therapeutic area and linker. This is anticipated to sustain the demand for antibody drug conjugates, resulting in lucrative monetization opportunities for players engaged in the antibody drug conjugates market.
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