Bosses remain the heart of Borderlands 4 farming culture, and each one has distinct loot pools that reward players who master their mechanics. Targeting the right bosses ensures consistent access to powerful, high-DPS weapons.

The Warbringer of Pandora is one of the first bosses worth farming. It’s a mechanical brute with predictable attack patterns and a high chance to drop Borderlands 4 Cash for sale explosive assault rifles. Its lair respawns quickly, making it perfect for repetitive runs.

In contrast, the Eternal Marauder found in the Promethea Docks drops elemental sniper rifles and pistols with chain-lightning effects. The fight is challenging due to shield phases, but patient players are rewarded with some of the best precision weapons in the game.

The Crimson Matriarch in the Vault of Queens is known for its rare Borderlands 4 Items shotgun drops. This boss has multiple loot tables, meaning each defeat could yield a completely different legendary weapon.

If you prefer fast runs, Drakon the Reborn in the Eridium Wastes is the best option. With a short respawn timer and weak points exposed during its transformation phase, it’s ideal for speed-oriented farming.

For late-game efficiency, target The Iron Wraith, whose loot pool includes unique heavy weapons with armor-piercing properties. These guns excel in endgame content like raids and elite skirmishes.

To improve results, use a boss rotation strategy, alternating between quick bosses and high-yield ones. This prevents loot fatigue and keeps the grind fresh.

Understanding which boss drops which weapon allows players to customize their farming goals. With precision farming, high-DPS weapons become attainable even for solo players.