Endgame Viability
Items with Greater Affixes are often more endgame viable than those with Diablo 4 Items regular affixes. As you progress through Diablo IV, the difficulty of enemies scales up, and you need stronger gear to keep up. Since Greater Affixes give higher stat values, they’re perfect for pushing through tougher content, Raids, or Uber Bosses.

High-tier content players will want to target items with Greater Affixes to ensure their builds can handle the toughest challenges the game throws at them.

6. Ease of Progression
Since Greater Affixes give a significant stat boost from the start, you can focus your resources on fine-tuning your build, rather than endlessly farming for the perfect affix rolls. This boosts the overall value of your items because they allow for more efficient and meaningful progression.

For example, if you’re aiming for maximum damage output for a Rogue or Sorcerer, the addition of a Greater Affix for Intelligence or Dexterity can make a much bigger impact than relying on several lesser, regular affixes.

Example of Increased Item Value in Action:
Let’s say you're playing a Druid and focusing on Shapeshifting. You want items that enhance your damage and survivability.

A regular item might give you +5% to damage and +50 Vitality.

A Greater Affix on the same item could give you +7.5% to damage and +75 Vitality, a 50% increase in both stats.

The increase in both damage and survivability makes the item much more valuable, especially when combined with Masterwork upgrades or Temper enhancements that focus on other stats like armor or cheap Diablo IV Items resistances.