Understanding IGF-1 DES IGF-1 DES (Insulin-like Growth Factor-1 DES(1-3)) is a truncated variant of IGF-1, missing the first three amino acids at the N-terminus. This molecular modification enhances its biological activity, resulting in significantly stronger anabolic effects than standard IGF-1. Its shorter half-life, approximately 20–30 minutes, makes it highly localized in action,...