The Epidermal Growth Factor Receptor (EGFR) is a transmembrane protein involved in vital cellular processes, including proliferation and survival. In many types of cancer, especially those of epithelial origin, abnormalities in EGFR expression or function contribute to tumor development and progression. Targeted therapies aimed at blocking EGFR have become a critical part of the cancer...

Mismatch Repair Deficiency (dMMR) emerges as a transformative biomarker highlighting disruptions in DNA error-correction mechanisms during cellular replication. When these protective systems malfunction, genetic aberrations proliferate, triggering genomic chaos and amplifying cancer development risks. This biomarker demonstrates particular significance across colorectal, endometrial, and...